# Adaptive Radiotherapy for Carcinoma Endometrium With Lymphocele: A Case Report

**Authors:** Induni N Weerarathna, Ashish Uke, Manishimwe Jules, Shweta B Dahake, Anurag Luharia

PMC · DOI: 10.7759/cureus.65775 · 2024-07-30

## TL;DR

This case report describes the successful use of adaptive radiotherapy in treating a high-grade endometrial cancer patient with a lymphocele.

## Contribution

The report highlights the unusual and positive response of a lymphocele to adaptive radiotherapy in a complex endometrial carcinoma case.

## Key findings

- Adaptive radiotherapy effectively managed a high-grade endometrial carcinoma in a 75-year-old patient.
- The patient's lymphocele showed a remarkable response to radiation therapy, indicating potential for adaptive approaches in similar cases.

## Abstract

The case report details the adaptive radiotherapy management of a 75-year-old female diagnosed with high-grade endometrial carcinoma. The patient, who was known to be hypertensive with no other comorbidities and no family history of cancer, presented with a complaint of bleeding per vagina for six months. Following extensive investigations, she underwent a laparoscopic radical hysterectomy. Postoperative histopathology confirmed endometrial adenocarcinoma International Federation of Gynecology and Obstetrics (FIGO) stage IA, grade III. The adjuvant treatment plan included adjuvant chemoradiotherapy to the postoperative tumor bed and draining lymph nodes. On planning computed tomography (CT), the patient’s lymphocele responded remarkably to radiation therapy, an unusual outcome that underscores the potential efficacy of adaptive radiotherapy in complex cases.

## Linked entities

- **Diseases:** endometrial carcinoma (MONDO:0002447)

## Full-text entities

- **Diseases:** FIGO (MESH:D005831), bleeding per vagina (MESH:D014625), hypertensive (MESH:D006973), Carcinoma Endometrium (MESH:D016889), Lymphocele (MESH:D008210), cancer (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11361454/full.md

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Source: https://tomesphere.com/paper/PMC11361454