# Using real-world evidence to complement evidence from randomized controlled trials on oral anticoagulants for stroke prevention

**Authors:** Mark J. R. Smeets, Suzanne C. Cannegieter

PMC · DOI: 10.1371/journal.pmed.1004449 · 2024-08-29

## TL;DR

This paper explores how real-world data can support clinical trial findings for anticoagulants used in stroke prevention.

## Contribution

The paper highlights the value of real-world evidence in complementing traditional clinical trial data for anticoagulant evaluation.

## Key findings

- Real-world data can provide insights into anticoagulant effectiveness in diverse patient populations.
- Complementing clinical trials with real-world evidence may improve understanding of long-term outcomes.

## Abstract

Mark J. R. Smeets and Suzanne C. Cannegieter discuss the use of real world data to complement data generated by clinical trials of systemic anticoagulants.

## Linked entities

- **Diseases:** stroke (MONDO:0005098)

## Full-text entities

- **Diseases:** stroke (MESH:D020521)

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Source: https://tomesphere.com/paper/PMC11361432