# Bilateral Global Nephrocalcinosis in a Uremic Puppy

**Authors:** Maria Rizzo, Melissa Pennisi, Francesco Macrì, Annastella Falcone, Simona Di Pietro, Kamel Mhalhel, Elisabetta Giudice

PMC · DOI: 10.3390/vetsci11080338 · Veterinary Sciences · 2024-07-25

## TL;DR

This paper reports a rare case of severe kidney disease in a young dog, highlighting the challenges in diagnosing and treating nephrocalcinosis.

## Contribution

The study presents a novel case of bilateral nephrocalcinosis in a 50-day-old puppy with uremic syndrome, emphasizing diagnostic and management challenges.

## Key findings

- A 50-day-old puppy presented with severe renal failure and bilateral nephrocalcinosis.
- Despite intensive care, the puppy's condition worsened rapidly, leading to euthanasia.
- The study calls for further research to improve treatment outcomes for young animals with nephrocalcinosis.

## Abstract

This study explores kidney disease in young dogs, focusing on early diagnosis, management, and the importance of staging for effective treatment. Highlighting mineral metabolism imbalances and complications like nephrocalcinosis, the study presents a case of severe renal failure with uremic syndrome and bilateral nephrocalcinosis in a 50-day-old puppy. Despite intensive care, the puppy’s condition worsened rapidly, leading to euthanasia. The study underscores the challenges in diagnosing and managing canine nephrocalcinosis in young animals. It emphasizes the need for further research to improve the understanding and treatment outcomes in such cases, enhancing the quality of life for animals suffering from this rare condition.

This study explores kidney disease in young dogs, focusing on early diagnosis, management, and the importance of staging for effective treatment. Highlighting mineral metabolism imbalances and complications such as nephrocalcinosis, the study presents a case of severe renal failure with uremic syndrome and bilateral nephrocalcinosis in a 50-day-old puppy. Despite intensive care, the puppy’s condition deteriorated rapidly, leading to euthanasia. The study underscores the challenges in diagnosing and managing canine nephrocalcinosis in young animals. It emphasizes the need for further research to improve the understanding and treatment outcomes in such cases, ultimately enhancing the quality of life for animals suffering from this rare condition.

## Linked entities

- **Diseases:** nephrocalcinosis (MONDO:0001567), renal failure (MONDO:0001106)
- **Species:** Canis lupus familiaris (taxon 9615)

## Full-text entities

- **Diseases:** renal failure (MESH:D051437), Uremic Puppy (MESH:D006463), Nephrocalcinosis (MESH:D009397), kidney disease (MESH:D007674)
- **Species:** Canis lupus familiaris (dog, subspecies) [taxon 9615]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11359828/full.md

## References

34 references — full list in the complete paper: https://tomesphere.com/paper/PMC11359828/full.md

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Source: https://tomesphere.com/paper/PMC11359828