# Wide Dynamic Range Digital Aberration Measurement and Fast Anterior-Segment OCT Imaging

**Authors:** Mengyuan Ke, Abhishek Kumar, Thor E. Ansbæk, Rainer A. Leitgeb

PMC · DOI: 10.3390/s24165161 · Sensors (Basel, Switzerland) · 2024-08-10

## TL;DR

This paper introduces a new system that measures eye aberrations over a wide range and provides fast imaging of the eye's front part.

## Contribution

The novel contribution is a dual-modality OCT system with extended defocus range and high-speed imaging capabilities.

## Key findings

- The system achieves a 20 D defocus dynamic range in aberration measurement.
- It provides anterior segment imaging at an A-scan rate of 1.6 MHz.
- Badal-like precompensation extends the dynamic range of digital wavefront aberrometry.

## Abstract

Ocular aberrometry with a wide dynamic range for assessing vision performance and anterior segment imaging that provides anatomical details of the eye are both essential for vision research and clinical applications. Defocus error is a major limitation of digital wavefront aberrometry (DWA), as the blurring of the detected point spread function (PSF) significantly reduces the signal-to-noise ratio (SNR) beyond the ±3 D range. With the aid of Badal-like precompensation of defocus, the dynamic defocus range of the captured aberrated PSFs can be effectively extended. We demonstrate a dual-modality MHz VCSEL-based swept-source OCT (SS-OCT) system with easy switching between DWA and OCT imaging modes. The system is capable of measuring aberrations with defocus dynamic range of 20 D as well as providing fast anatomical imaging of the anterior segment at an A-scan rate of 1.6 MHz.

## Full-text entities

- **Diseases:** error (MESH:D012030), eye diseases (MESH:D005128), ocular aberrations (MESH:D002869), cataract (MESH:D002386), injury to people or property (MESH:C000719191), glaucoma (MESH:D005901)
- **Chemicals:** PSF (-), water (MESH:D014867), DAO (MESH:C030358), silica (MESH:D012822)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Cell lines:** S2 — Drosophila melanogaster (Fruit fly), Spontaneously immortalized cell line (CVCL_Z232)

## Full text

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## Figures

13 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11359324/full.md

## References

26 references — full list in the complete paper: https://tomesphere.com/paper/PMC11359324/full.md

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Source: https://tomesphere.com/paper/PMC11359324