Biological and Physical Characterization of Surface-Modified Grade V Titanium Alloy
Mahesh Kakunje, Supriya Nambiar, Arun M. Isloor, Shamaprasada Kabekkodu, Udaya Bhat
TL;DR
This study examines how different surface modifications affect the physical and biological properties of titanium alloy, finding that polydopamine coatings offer the best performance for potential implant applications.
Contribution
The study provides a direct comparison of multiple surface modification techniques on titanium alloy for their physical and biological performance.
Findings
Polydopamine-coated titanium showed the best physical and biological properties.
Smother surfaces increased fibroblast adhesion compared to rougher surfaces.
Chitosan and acid-etched surfaces had higher wettability than sandblasted ones.
Abstract
Surface modification and biomimetic approaches have been widely used to enhance bioinert substances. It is not very clear whether surface alterations and polymer coatings on titanium make it more biologically active and enhance cell adhesion. We tried to focus on the physical and biological characterization of surface-modified titanium disks. Four different surface modifications were done for the titanium disks, ranging from acid etching, sandblasting, polydopamine coating, and polydopamine-based chitosan coating, and were compared with disks without any surface modification. The disks were studied for physical characteristics like surface roughness and contact angle. Human gingival fibroblasts were used to investigate the biological effects of surface modification of titanium alloy surfaces. The wettability of chitosan-coated, acid-etched, and polydopamine-coated titanium was much…
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Taxonomy
TopicsPolymer Surface Interaction Studies · Bone Tissue Engineering Materials · Electrospun Nanofibers in Biomedical Applications