The Role of Postbiotics in Asthma Treatment

TL;DR

This review explores how postbiotics, non-living microorganisms, may help treat asthma by modulating the immune system and reducing flare-ups.

Contribution

The paper highlights the novel potential of postbiotics in asthma treatment through their immunomodulating effects.

Findings

Postbiotics can alter immune responses in allergic asthma patients.

They may reduce asthma exacerbations by modulating reactions to allergens and pathogens.

More research is needed to integrate postbiotics into clinical asthma treatment.

Abstract

In recent years, there has been abundant research concerning human microbiome and its impact on the host’s health. Studies have shown that not only the commensal bacteria itself, but also postbiotics, understood as inanimate microorganisms, possibly with the presence of their components, may themselves have an effect on various elements of human physiology. In this review, we take a closer look at the specific ways in which postbiotics can alter immune response in allergic asthma, which is one of the most prevalent allergic diseases in today’s world and a serious subject of concern. Through altering patients’ immune response, not only to allergens but also to pathogens, postbiotics could have a significant role in lowering the number of asthma exacerbations. We suggest that more profound research should be undertaken in order to launch postbiotics into clinical standards of asthma treatment, given the greatly promising findings in terms of their immunomodulating potential.

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