Utilization of Head Imaging in Children and Adolescents With First-Episode Psychosis: A Retrospective Analysis

TL;DR

This study examines how often head imaging is used in children and teens with first-time psychosis and finds it's rare and doesn't often reveal non-psychiatric causes.

Contribution

The study provides evidence supporting a conservative approach to head imaging in pediatric first-episode psychosis.

Findings

Only 10.6% of pediatric patients with first-episode psychosis received head imaging.

CT scans were the modality used, but no significant neurological findings were detected.

African American or Black patients were more likely to receive head imaging.

Abstract

Background

Psychotic disorders are commonly diagnosed in the mid-20s but symptoms often emerge earlier during late teenage years to mid-20s. Notably, studies have shown that psychotic symptoms can also affect younger individuals, with a higher prevalence among preteens than teens. Head imaging via computed tomography (CT) or magnetic resonance imaging (MRI) can be performed to rule out non-psychiatric causes of psychotic symptoms in this population but may pose additional risks and financial burdens. Practice patterns vary regarding when to utilize head imaging in pediatric patients with first-episode psychosis (FEP). The purpose of this study is to better understand the use of head imaging in pediatric FEP and associated patient characteristics.

Methods

A retrospective cohort study was performed. Eligible patients were <18 years of age with an encounter documented between 2013 and 2023 where a diagnosis code for psychosis was first applied. Medical records were manually reviewed if head imaging was performed during the index encounter or within one month. Descriptive statistics were used to report the study population demographics. Independent t-testing was used to compare characteristics between patients who did and did not receive head imaging.

Results

A total of 113 patients met the inclusion criteria for the study, of which 12 (10.6%) received head imaging within the specified timeframe. All received CT criteria head scans, and a significantly higher proportion were African American or Black when compared to those who did not receive head imaging (10/12 (83.3%) vs. 53/101 (52.5%) p=0.023). None of the imaging tests performed yielded significant neurological findings that suggested an underlying pathology for psychosis.

Conclusions

Head imaging was rarely utilized for the initial assessment of pediatric FEP in this study. When it was used, CT head scans were the modality of choice but did not yield any remarkable findings to suggest a non-psychiatric cause of psychotic symptoms. This adds to the body of evidence supporting a conservative approach when considering head imaging in pediatric FEP.