# Novel Hybrid Quantum Architecture-Based Lung Cancer Detection Using Chest Radiograph and Computerized Tomography Images

**Authors:** Jason Elroy Martis, Sannidhan M S, Balasubramani R, A. M. Mutawa, M. Murugappan

PMC · DOI: 10.3390/bioengineering11080799 · Bioengineering · 2024-08-07

## TL;DR

This paper introduces a new hybrid system combining deep learning and quantum computing to detect lung cancer from chest and CT images with high accuracy.

## Contribution

The novel contribution is a hybrid quantum computing and deep learning framework for improved lung cancer detection.

## Key findings

- The system achieved 92.12% overall accuracy in lung cancer detection.
- It outperformed traditional methods in sensitivity, specificity, F1-score, and precision.
- Quantum computing enhanced processing speed and scalability for early cancer screening.

## Abstract

Lung cancer, the second most common type of cancer worldwide, presents significant health challenges. Detecting this disease early is essential for improving patient outcomes and simplifying treatment. In this study, we propose a hybrid framework that combines deep learning (DL) with quantum computing to enhance the accuracy of lung cancer detection using chest radiographs (CXR) and computerized tomography (CT) images. Our system utilizes pre-trained models for feature extraction and quantum circuits for classification, achieving state-of-the-art performance in various metrics. Not only does our system achieve an overall accuracy of 92.12%, it also excels in other crucial performance measures, such as sensitivity (94%), specificity (90%), F1-score (93%), and precision (92%). These results demonstrate that our hybrid approach can more accurately identify lung cancer signatures compared to traditional methods. Moreover, the incorporation of quantum computing enhances processing speed and scalability, making our system a promising tool for early lung cancer screening and diagnosis. By leveraging the strengths of quantum computing, our approach surpasses traditional methods in terms of speed, accuracy, and efficiency. This study highlights the potential of hybrid computational technologies to transform early cancer detection, paving the way for wider clinical applications and improved patient care outcomes.

## Linked entities

- **Diseases:** lung cancer (MONDO:0005138)

## Full-text entities

- **Diseases:** cancer (MESH:D009369), Lung Cancer (MESH:D008175)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

10 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11351577/full.md

## References

50 references — full list in the complete paper: https://tomesphere.com/paper/PMC11351577/full.md

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Source: https://tomesphere.com/paper/PMC11351577