# Deciphering Factors Contributing to Cost-Effective Medicine Using Machine Learning

**Authors:** Bowen Long, Jinfeng Zhou, Fangya Tan, Srikar Bellur

PMC · DOI: 10.3390/bioengineering11080818 · Bioengineering · 2024-08-12

## TL;DR

This study uses machine learning to find factors that make over-the-counter medicines cost-effective for consumers.

## Contribution

A novel cost-effectiveness rating (CER) was developed using user ratings and prices from Amazon.

## Key findings

- FSA/HSA eligibility, symptom range, and packaging size significantly affect cost-effectiveness.
- Cold medicines with safety warnings are cost-effective due to lower prices and effective ingredients.
- Kid-friendly allergy meds and specific ingredients boost cost-effectiveness in different medication categories.

## Abstract

This study uses machine learning to identify critical factors influencing the cost-effectiveness of over-the-counter (OTC) medications. By developing a novel cost-effectiveness rating (CER) based on user ratings and prices, we analyzed data from Amazon. The findings indicate that Flexible Spending Account (FSA)/Health Savings Account (HSA) eligibility, symptom treatment range, safety warnings, special effects, active ingredients, and packaging size significantly impact cost-effectiveness across cold, allergy, digestion, and pain relief medications. Medications eligible for FSA or HSA funds, treating a broader range of symptoms, and having smaller packaging are perceived as more cost-effective. Cold medicines with safety warnings were cost-effective due to their lower average price and effective ingredients like phenylephrine and acetaminophen. Allergy medications with kid-friendly features showed higher cost-effectiveness, and ingredients like calcium, famotidine, and magnesium boosted the cost-effectiveness of digestion medicines. These insights help consumers make informed purchasing decisions and assist manufacturers and retailers in enhancing product competitiveness. Overall, this research supports better decision-making in the pharmaceutical industry by highlighting factors that drive cost-effective medication purchases.

## Linked entities

- **Chemicals:** phenylephrine (PubChem CID 4782), acetaminophen (PubChem CID 1983), calcium (PubChem CID 5460341), famotidine (PubChem CID 5702160), magnesium (PubChem CID 5462224)

## Full-text entities

- **Diseases:** cold (MESH:D000067390), Allergy (MESH:D004342), pain (MESH:D010146)

## Full text

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## Figures

18 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11351455/full.md

## References

45 references — full list in the complete paper: https://tomesphere.com/paper/PMC11351455/full.md

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Source: https://tomesphere.com/paper/PMC11351455