# Delirious Mania in a 77-Year-Old Female

**Authors:** Eduardo D Espiridion, Ashley Deng, Lily Charron

PMC · DOI: 10.7759/cureus.65619 · Cureus · 2024-07-29

## TL;DR

A 77-year-old woman showed signs of delirious mania, a rare condition combining delirium and manic symptoms, alongside a diagnosis of acute metabolic encephalopathy.

## Contribution

This case report adds to the limited literature on delirious mania by describing a unique clinical presentation in an elderly patient.

## Key findings

- The patient exhibited symptoms of delirium and mania, including confusion, inappropriate laughter, and agitation.
- Delirious mania was considered in the differential diagnosis despite a primary diagnosis of acute metabolic encephalopathy.
- The case highlights the rarity and diagnostic challenges of delirious mania in elderly populations.

## Abstract

Delirium is associated with acute episodes of disturbances in attention and awareness along with changes to cognition, including memory deficits and disorientation. Delirious mania (DM) is an unusual phenomenon where symptoms of delirium co-exist with symptoms of mania such as elevated or irritable mood, grandiosity, agitation, and cognitive disorganization. There is no formal agreement upon clinical symptoms for DM, but it generally includes acute onset of confusion, poor orientation, excitation, restlessness, and delusions. DM was first identified in the mid-1800s by Dr. Luther Bell and has only been identified by case reports since. We investigated a 77-year-old woman who was found at a gas station in an altered mental state. Upon observation, she has symptoms consistent with DM, including inappropriate laughter, distraction and confusion. She was diagnosed with acute metabolic encephalopathy, but the presentation of DM was considered in the differential and remains a unique finding.

## Full-text entities

- **Diseases:** irritable mood (MESH:D019964), agitation (MESH:D011595), cognitive disorganization (MESH:D003072), confusion (MESH:D003221), disturbances in attention and awareness (MESH:D058926), Delirium (MESH:D003693), delusions (MESH:D063726), DM (MESH:D001714), memory deficits (MESH:D008569), metabolic encephalopathy (MESH:D001928), poor orientation (MESH:D016773)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC11350395/full.md

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Source: https://tomesphere.com/paper/PMC11350395