# Primary Pulmonary Hodgkin's Lymphoma Revealed by a Cavitary Lung Lesion: A Case With an Atypical Presentation and Literature Review

**Authors:** Boujemaa Razouq, Mouhsin Ibba, Mohamed Mahdaoui, Meryem El Ouazzani, Hicham Fenane, Yassine Msougar

PMC · DOI: 10.7759/cureus.65479 · Cureus · 2024-07-26

## TL;DR

This case report describes a rare lung cancer that initially appeared as a cavitary lesion, leading to diagnostic confusion before being correctly identified.

## Contribution

The paper presents a rare case of primary pulmonary Hodgkin's lymphoma with an atypical cavitary presentation and emphasizes its diagnostic challenges.

## Key findings

- PPHL can mimic infectious diseases like tuberculosis or pneumonia, delaying diagnosis.
- Surgical resection was necessary to confirm the diagnosis after initial tests failed.
- PPHL should be considered in the differential diagnosis of cavitary lung lesions.

## Abstract

Primary pulmonary Hodgkin's lymphoma (PPHL) is an uncommon condition that accounts for less than 1% of all lymphomas. The clinical and radiological presentation of PPHL is nonspecific. This case report aimed to highlight the misleading presentation of PPHL, which initially manifested as a pulmonary cavitary lesion. The presented case report describes a perplexing presentation of PPHL in a 24-year-old female patient. Initially suspected to have necrotizing pneumonia or pulmonary tuberculosis due to symptoms including cough, hemoptysis, and weight loss, the patient underwent various diagnostic procedures, including bronchoscopy and CT-guided biopsy, which failed to provide a definitive diagnosis. Surgical resection was eventually pursued, leading to the conclusive identification of PPHL. This case highlights the diagnostic challenges associated with PPHL, emphasizing the importance of considering this rare entity in the differential diagnosis of pulmonary nodular or cavitary lesions. Prompt recognition and accurate diagnosis are essential for optimal management and improved patient outcomes. PPHL is an infrequent neoplasm that often presents diagnostic dilemmas. It requires consideration within the appropriate clinical framework to ensure timely diagnosis and intervention.

## Linked entities

- **Diseases:** Hodgkin's lymphoma (MONDO:0004952), pulmonary tuberculosis (MONDO:0006052)

## Full-text entities

- **Diseases:** Cavitary Lung Lesion (MESH:D008171), hemoptysis (MESH:D006469), pulmonary tuberculosis (MESH:D014397), necrotizing pneumonia (MESH:D000071067), cough (MESH:D003371), lymphomas (MESH:D008223), weight loss (MESH:D015431), PPHL (MESH:D006689), neoplasm (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11346744/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC11346744/full.md

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Source: https://tomesphere.com/paper/PMC11346744