# Hypokalemic Quadriparesis Associated With Renal Glycosuria in Dengue Fever: A Rare Presentation

**Authors:** Jay Kakadiya, Kush Varsadiya, Chintan Kakadiya, Maulik Prajapati, Pritesh Patel

PMC · DOI: 10.7759/cureus.65489 · 2024-07-27

## TL;DR

A rare case of dengue fever is reported with hypokalemic quadriparesis and renal glycosuria, suggesting a possible new mechanism for these symptoms.

## Contribution

The paper proposes a novel mechanism linking hypokalemia and renal glycosuria in dengue fever.

## Key findings

- A case of dengue fever presented with hypokalemia and renal glycosuria.
- The proposed mechanism may explain both hypokalemia and renal glycosuria in dengue patients.

## Abstract

Dengue fever is a viral hemorrhagic fever mainly transmitted by Aedes mosquitoes and is especially prevalent in equatorial regions. The presentation of dengue fever can range from mild symptoms, such as fever and body aches, to severe symptoms, such as hemorrhagic bleeding and shock. Although it is a non-neurotropic virus, it rarely manifests as a neurological abnormality. Previous data suggests that the incidence of electrolyte disturbance is increasing in patients with dengue. Here, we have described a case of dengue fever with hypokalemia and renal glycosuria. Studies show that the probable mechanism of developing hypokalemia is increased insulin and catecholamine, but it is still not well-established. We propose a mechanism that can explain both hypokalemia and renal glycosuria in our case.

## Linked entities

- **Diseases:** dengue fever (MONDO:0005502), hypokalemia (MONDO:0003019), renal glycosuria (MONDO:0009297)

## Full-text entities

- **Genes:** INS (insulin) [NCBI Gene 3630] {aka IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10}
- **Diseases:** shock (MESH:D012769), body aches (MESH:D010146), hemorrhagic bleeding (MESH:D006470), viral hemorrhagic fever (MESH:D006482), fever (MESH:D005334), Dengue Fever (MESH:D003715), hypokalemia (MESH:D007008), Renal Glycosuria (MESH:D006030), neurological abnormality (MESH:D009461), Hypokalemic Quadriparesis (MESH:D011782)
- **Chemicals:** catecholamine (MESH:D002395)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11345617/full.md

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Source: https://tomesphere.com/paper/PMC11345617