# A Case Report of Schizophrenia With a Partially Empty Sella: Related or Incidental?

**Authors:** Anshita Girdhar, Pradeep S Patil

PMC · DOI: 10.7759/cureus.65322 · 2024-07-25

## TL;DR

A 55-year-old man with schizophrenia and a partially empty sella raises questions about a possible link between the two conditions.

## Contribution

This case report suggests a potential relationship between schizophrenia and a partially empty sella, which is rarely discussed in the literature.

## Key findings

- The patient's MRI showed a partially empty sella alongside schizophrenia symptoms.
- Few existing studies have explored the correlation between schizophrenia and a partially empty sella.
- Further research is needed to determine if the two conditions are causally related.

## Abstract

A 55-year-old male patient who had a history of schizophrenia for 20 years was admitted to the Department of Psychiatry, in a tertiary care center. The patient presented with an exacerbation of symptoms for three months, with no apparent cause, leading to the suspicion of an underlying organic cause. The patient was overweight, was newly diagnosed as a case of type 2 diabetes mellitus, and also had swelling over his left ear. The magnetic resonance imaging (MRI) brain and laboratory testing that were done while he was in the hospital revealed the existence of a partially empty sella. With the MRI findings, it can be said that the partially empty sella and the occurrence of schizophrenia can be related to each other. In the existing literature, a few studies indicate the correlation between the two, and future studies can help with identifying the association.

## Linked entities

- **Diseases:** schizophrenia (MONDO:0005090), type 2 diabetes mellitus (MONDO:0005148)

## Full-text entities

- **Diseases:** swelling (MESH:D004487), Schizophrenia (MESH:D012559), type 2 diabetes mellitus (MESH:D003924), Empty Sella (MESH:D004652), overweight (MESH:D050177)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11344622/full.md

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Source: https://tomesphere.com/paper/PMC11344622