# Comparison of Lipid Profiles Between Prediabetic and Non-prediabetic Young Adults

## TL;DR

This study compares lipid profiles in young adults with prediabetes and non-prediabetics, finding significant differences that may increase cardiovascular risk.

## Contribution

The study identifies specific lipid parameter changes in prediabetic young adults that could predict cardiovascular risk.

## Key findings

- Prediabetics had significantly higher total cholesterol, LDL, VLDL, and triglycerides compared to controls.
- Prediabetics showed significantly lower HDL cholesterol levels than non-prediabetic individuals.

## Abstract

Introduction

Insulin resistance is considered a key component in the pathophysiology of prediabetes. Derangement in lipid parameters can occur in prediabetics that predispose to cardiovascular complications.

Material and methods

We performed an observational cross-sectional analytical study in a tertiary level Acharya Vinoba Bhave hospital, Sawangi, Wardha to compare the lipid profile in prediabetics with non-prediabetic young individuals between 18 and 35 age group in terms of parameters such as total cholesterol, triglyceride (TG), low-density lipoproteins (LDL) cholesterol, very low-density lipoprotein (VLDL) cholesterol, and high-density lipoprotein (HDL) cholesterol.

Results

We observed that prediabetics have significantly elevated total cholesterol, LDL cholesterol, VLDL cholesterol, and TG; and significantly reduced HDL cholesterol compared with the controls (p<0.001 each).

Conclusion

We conclude that the lipid parameters are deranged in prediabetics and this might contribute to the risk associated with dyslipidemia in this population.