# Editorial: Advances in novel pharmacotherapeutics and drug discovery: computational, experimental, translational, and clinical models

**Authors:** Cristian Sandoval, Francisco Torrens, Vanessa Souza-Mello, Jorge Farías

PMC · DOI: 10.3389/fphar.2024.1465835 · Frontiers in Pharmacology · 2024-08-09

## Full-text entities

- **Genes:** CS (citrate synthase) [NCBI Gene 1431], PDCD1 (programmed cell death 1) [NCBI Gene 5133] {aka ADMIO4, AIMTBS, CD279, PD-1, PD1, SLEB2}, GARS1 (glycyl-tRNA synthetase 1) [NCBI Gene 2617] {aka CMT2D, DSMAV, GARS, GlyRS, HMN5, HMN5A}, IGHA1 (immunoglobulin heavy constant alpha 1) [NCBI Gene 3493] {aka IgA1}, FMR1 (fragile X messenger ribonucleoprotein 1) [NCBI Gene 2332] {aka FMRP, FRAXA, POF, POF1}, CTLA4 (cytotoxic T-lymphocyte associated protein 4) [NCBI Gene 1493] {aka ALPS5, CD, CD152, CELIAC3, CTLA-4, GRD4}, DES (desmin) [NCBI Gene 1674] {aka CDCD3, CSM1, CSM2, LGMD1D, LGMD1E, LGMD2R}
- **Diseases:** kidney damage (MESH:D007674), cancer (MESH:D009369), mitochondrial damage (MESH:D028361), Non-small-cell lung cancer (MESH:D002289), hearing loss (MESH:D034381), Fragile X Syndrome (MESH:D005600), intellectual impairments (MESH:C565406), hyperlipidemia (MESH:D006949), cytotoxicity (MESH:D064420), Lung cancer (MESH:D008175), ototoxicity (MESH:D006311), autism spectrum disease (MESH:D000067877)
- **Chemicals:** Cisplatin (MESH:D002945), tetrandrine (MESH:C009438), platinum (MESH:D010984), cholesterol (MESH:D002784), triglyceride (MESH:D014280), GABA (MESH:D005680), Fraisinib (-)
- **Species:** Bambuseae (bamboo, tribe) [taxon 147376], Pinellia ternata (species) [taxon 199225], Zingiber officinale (ginger, species) [taxon 94328], Rattus norvegicus (brown rat, species) [taxon 10116], Mus musculus (house mouse, species) [taxon 10090], Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

4 references — full list in the complete paper: https://tomesphere.com/paper/PMC11341978/full.md

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Source: https://tomesphere.com/paper/PMC11341978