# A Fleshy Mystery: Prurigo Nodularis

**Authors:** Jianna Bona, Micah Pippin, Logan Atkins, Majeed Al-Quraishi

PMC · DOI: 10.7759/cureus.65125 · Cureus · 2024-07-22

## TL;DR

This paper presents a case of prurigo nodularis, a chronic skin condition causing severe itching and nodules, and discusses its clinical features and management.

## Contribution

The paper contributes a detailed case report and literature review to better understand the clinical approach to prurigo nodularis.

## Key findings

- Prurigo nodularis is diagnosed clinically based on chronic pruritus and characteristic lesions.
- Management focuses on reducing pruritus and skin irritation, though treatment remains challenging.
- The case highlights the impact of the disease on quality of life and the need for ongoing care.

## Abstract

Prurigo nodularis is a chronic dermatologic condition typically presenting as firm, dome-shaped pruritic nodules of various sizes that are often symmetrically distributed on extensor surfaces of the extremities. The diagnosis is clinical and based on a history of chronic, severe pruritis in the setting of characteristic, excoriated lesions. Treatment is difficult and aimed at reducing skin irritation and pruritus. Quality of life is impacted due to the chronic, intractable, and relapsing nature of the disease. Here, we report a case of prurigo nodularis diagnosed in the outpatient clinic setting. This paper aims to report the patient's clinical history, presentation, and histopathologic findings, as well as present a literature review to determine the significance of this case and the approach to ongoing management.

## Linked entities

- **Diseases:** prurigo nodularis (MONDO:0026045)

## Full-text entities

- **Diseases:** dermatologic condition (MESH:D000168), Prurigo nodularis (MESH:D011536), pruritis (MESH:D011537), skin irritation (MESH:D012871)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11338647/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC11338647/full.md

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Source: https://tomesphere.com/paper/PMC11338647