# Unveiling Oral Malignant Melanoma: Clinicopathological Details of a Case

**Authors:** Saptarshi Das, Rojina Pervin, Sanjeet K Das, Arunit Chatterjee, Sudeshna Bagchi

PMC · DOI: 10.7759/cureus.65101 · Cureus · 2024-07-22

## TL;DR

This paper presents a case of oral malignant melanoma, emphasizing the importance of early diagnosis due to its poor prognosis and rarity.

## Contribution

The paper contributes a detailed clinicopathological case report highlighting diagnostic challenges and the need for early detection.

## Key findings

- Oral malignant melanoma is rare and often diagnosed late, leading to poor survival rates.
- The case involved a 54-year-old male with a pigmented lesion confirmed as oral malignant melanoma via biopsy and IHC.
- PET-CT scan showed widespread metastasis, underscoring the aggressive nature of the disease.

## Abstract

Oral malignant melanoma is a rare tumor of the oral cavity. It is more common among Negros and Japanese people. Initial symptoms are frequently overlooked, resulting in a delayed diagnosis and poor prognosis with a 5-year survival rate. Unlike melanomas in other sites, it is uncommon and thus lacks a well-defined classification system and treatment regimen. The survival rate is mainly correlated with early diagnosis and treatment. A 54-year-old male reported to our department with a de novo fast-growing exophytic proliferative pigmented lesion for six months. After proper radiographic analysis, an incisional biopsy was done which revealed the presence of nests and fascicles of pleomorphic spindle cells with hyperchromatic nuclei and abundant brown pigments rendering it a provisional diagnosis of oral malignant melanoma which was later confirmed by immunohistochemistry (IHC). PET-CT scan revealed widespread metastasis. This article stresses the importance of identification of initial symptoms which are frequently overlooked, resulting in a delayed diagnosis and poor prognosis.

## Full-text entities

- **Diseases:** tumor of the oral cavity (MESH:D009062), Oral Malignant Melanoma (MESH:D008545), proliferative pigmented lesion (MESH:D010859), metastasis (MESH:D009362)

## Full text

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## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11337979/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC11337979/full.md

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Source: https://tomesphere.com/paper/PMC11337979