# Multinodal Cervical Angiomyomatous Hamartoma

**Authors:** Georgia Mackay, James Johnston, Sameer Mallick, Vinod Khanijow

PMC · DOI: 10.1177/10668969231212429 · International Journal of Surgical Pathology · 2023-11-20

## TL;DR

This paper describes a rare case of a benign tumor found in multiple neck lymph nodes, which is unusual for this type of lesion.

## Contribution

The novelty lies in presenting the first reported case of multinodal cervical angiomyomatous hamartoma.

## Key findings

- MRI showed intermediate T1 and high T2 enhancement with post-gadolinium enhancement.
- Histological features included central nodal distribution, muscular vessel walls, and adipose tissue.
- The lesion was HMB45 negative, distinguishing it from other vascular lesions.

## Abstract

Angiomyomatous hamartoma (AMH) is a rare benign lesion of the lymph nodes. Angiomyomatous hamartoma tends to be found in inguinal lymph nodes, and usually in a single lymph node. We present a rare care case of a 53-year-old presenting with a neck lump, found to be AMH involving multiple lymph nodes in her neck. To our knowledge, this is the first case presenting with multiple nodes in this location. There are a limited number of case reports describing magnetic resonance imaging (MRI) features of AMH lesions located in inguinal and head and neck regions. Our MRI findings revealed the mass had intermediate T1 enhancement, high T2 signal enhancement, and high post-gadolinium enhancement and fat saturation of the lesion. Angiomyomatous hamartoma is a histological diagnosis, distinguished from other similar nodal vascular lesions by a number of key features: including the presence of central nodal distribution, muscular blood vessel walls, adipose tissue, and HMB45 negative staining. Early recognition of this benign lesion may have implications for a patient's clinical course and surgical requirements.

## Full-text entities

- **Diseases:** lymph (MESH:D000072717), neck lump (MESH:D006258), benign lesion (MESH:D001932), AMH (MESH:D006222), nodal vascular lesions (MESH:D014652)
- **Chemicals:** gadolinium (MESH:D005682)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11337725/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC11337725/full.md

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Source: https://tomesphere.com/paper/PMC11337725