Lateral Posterior Method for Depth Correction while Using the Gates Protocol for GFR Estimation: Is it Comparable to the Gold Standard GFR Estimation by Plasma Sampling?
Shefali Madhur Gokhale
TL;DR
This study compares a depth correction method for estimating kidney function using a gamma camera to a gold standard blood test method.
Contribution
The study evaluates the lateral posterior method for depth correction in GFR estimation using the Gates protocol.
Findings
No significant agreement was found between plasma sampling and gamma camera or lateral posterior methods.
Systemic bias was lower with the gamma camera method compared to the lateral posterior method.
Abstract
Background Glomerular filtration rate (GFR) estimation by Gates protocol using the gamma camera for diethylenetriaminepentaacetic acid (DTPA) dynamic renography has not compared well with the gold standard GFR by plasma sampling method. This is because depth of the kidneys is generally not considered. Our aim was to study whether manual depth correction using the skin to middle of kidney distance in lateral view and posterior aspect-lateral posterior method would reduce the bias in the Gates GFR as compared with the gold standard. Materials and Methods Retrospective study of 27 adult prospective renal donors who underwent GFR by plasma sampling and DTPA dynamic renography at Inlaks and Budhrani Hospital, Pune, Maharashtra, India between January 2022 and April 2023. The entire data was statistically analyzed using Statistical Package for Social Sciences (SPSS ver 21.0, IBM…
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Taxonomy
TopicsChronic Kidney Disease and Diabetes · MRI in cancer diagnosis · Pediatric Urology and Nephrology Studies