# 1,2-Difluoroethylene (HFO-1132): synthesis and chemistry

**Authors:** Liubov V Sokolenko, Taras M Sokolenko, Yurii L Yagupolskii

PMC · DOI: 10.3762/bjoc.20.171 · Beilstein Journal of Organic Chemistry · 2024-08-12

## TL;DR

This paper reviews the synthesis and chemical properties of 1,2-difluoroethylene (HFO-1132), including methods to make its isomers and how it reacts in different chemical processes.

## Contribution

The paper offers a comprehensive review of synthesis methods and chemical reactivity of HFO-1132 isomers.

## Key findings

- Major synthesis routes for E- and Z-isomers of HFO-1132 are reviewed.
- The reactivity of HFO-1132 in radical, nucleophilic, and electrophilic reactions is discussed.
- The paper provides insights into the chemical behavior of HFO-1132 under various conditions.

## Abstract

This article provides a comprehensive overview of the synthesis and chemistry of 1,2-difluoroethylene (HFO-1132). The major routes for the preparation of the E- and Z-isomer of HFO-1132 are reviewed, along with the chemistry in radical, nucleophilic, and electrophilic reactions.

## Linked entities

- **Chemicals:** 1,2-difluoroethylene (PubChem CID 5365501)

## Full text

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## Figures

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## References

110 references — full list in the complete paper: https://tomesphere.com/paper/PMC11331538/full.md

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Source: https://tomesphere.com/paper/PMC11331538