# Atypical presentation of Felty syndrome: Successful management with rituximab therapy—A case report and review of literature

**Authors:** Rabia Iqbal, Ana Colon‐Ramos, Zhenisa Hysenaj, Samridhi Sinha, Shahzaib Nabi, Sabrin Marowa

PMC · DOI: 10.1002/ccr3.9339 · Clinical Case Reports · 2024-08-18

## TL;DR

This case report highlights the atypical presentation of Felty syndrome and the importance of early diagnosis and treatment for better outcomes.

## Contribution

The paper presents a rare case of Felty syndrome without arthritis and emphasizes the role of rituximab therapy in its management.

## Key findings

- Felty syndrome can present atypically without arthritis symptoms.
- Timely diagnosis of neutropenia and splenomegaly is crucial for improved prognosis.
- Multidisciplinary collaboration is essential for accurate diagnosis and treatment.

## Abstract

The atypical presentation of Felty syndrome, even without arthritis symptoms, needs further evaluation. Timely diagnosis of neutropenia and splenomegaly in patients with rheumatoid arthritis without joint symptoms is crucial for a better prognosis. Despite the rarity of the condition, clinicians should have a high index of suspicion, and multidisciplinary collaboration between rheumatology, hematology, and other specialists is required for accurate diagnosis.

## Linked entities

- **Diseases:** Felty syndrome (MONDO:0007603), rheumatoid arthritis (MONDO:0008383), neutropenia (MONDO:0001475)

## Full-text entities

- **Diseases:** splenomegaly (MESH:D013163), rheumatoid arthritis (MESH:D001172), Felty syndrome (MESH:D005258), neutropenia (MESH:D009503), arthritis (MESH:D001168)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11331027/full.md

## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC11331027/full.md

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Source: https://tomesphere.com/paper/PMC11331027