# An Unusual Case Report of Male Genital Tuberculosis

**Authors:** Tamizharasan Masilamani, Nalini Jayanthi, Anitha Elaiyalwar, Karniha B, Shivasekar Ganapati

PMC · DOI: 10.7759/cureus.64950 · Cureus · 2024-07-19

## TL;DR

This paper reports three rare cases of testicular tuberculosis, highlighting the challenges in diagnosing this uncommon form of extrapulmonary TB.

## Contribution

The novelty lies in presenting three confirmed cases of isolated testicular tuberculosis, a rare manifestation of EPTB.

## Key findings

- Testicular tuberculosis was diagnosed using tissue biopsy and AFB smears.
- The condition is rare and often difficult to detect due to its pauci-bacillary nature.
- The report emphasizes the need for invasive diagnostic methods in such cases.

## Abstract

The burden of extrapulmonary tuberculosis (EPTB) is significant, constituting up to 20% of all TB cases in HIV-negative patients and 50% of new cases in HIV-positive individuals. However, diagnosing EPTB remains challenging due to its pauci-bacillary nature and the necessity for invasive sampling methods in many forms of the disease. Urogenital tuberculosis represents approximately 4% of the annual cases of extra-pulmonary tuberculosis in India, with isolated testicular tuberculosis being a particularly rare manifestation. In this report, we present three cases of testicular tuberculosis, diagnosed through tissue biopsy and Acid Fast Bacilli (AFB) smears.

## Linked entities

- **Diseases:** tuberculosis (MONDO:0018076), extrapulmonary tuberculosis (MONDO:0000368)

## Full-text entities

- **Diseases:** HIV (MESH:D015658), Genital Tuberculosis (MESH:D014376), EPTB (MESH:D000092225), TB (MESH:D014390), Urogenital tuberculosis (MESH:D014401)
- **Species:** Human immunodeficiency virus 1 (no rank) [taxon 11676], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11331003/full.md

## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC11331003/full.md

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Source: https://tomesphere.com/paper/PMC11331003