# Vertical Partial Laryngectomy With Temporoparietal Free‐Flap Reconstruction for Recurrent Laryngeal Cancer: Long‐Term Study

**Authors:** Sharon Tzelnick, John R. de Almeida, Ralph Gilbert, David Goldstein

PMC · DOI: 10.1002/oto2.179 · OTO Open · 2024-08-18

## TL;DR

This study shows that vertical partial laryngectomy is a long-term effective treatment for recurrent laryngeal cancer with good survival and quality of life.

## Contribution

The study provides long-term outcomes of vertical partial laryngectomy for recurrent laryngeal cancer, emphasizing its oncologic and functional benefits.

## Key findings

- 90% disease-specific survival and 80% overall survival were observed at 10 years.
- 70% of patients remained laryngectomy-free for 10 years.
- Local recurrences were successfully salvaged with total laryngectomy.

## Abstract

Treatment options for recurrent early glottic carcinoma's include conservative and radical surgical options. These options offer similar survival benefits with different impacts of patient's quality of life. We previously present our experience with vertical partial laryngectomy (VPL) and showed high locoregional control rates with high‐quality voice results and normal swallowing.

A long‐term retrospective review.

Tertiary Care Center.

We analyzed all patients underwent VPL between the years 1995 to 2018. Long‐term oncologic and functional outcomes were collected.

A total of 40 patients were included. The majority of whom were male (n = 38, 95%) with a mean age of 64.9 years (SD ± 9.5). With a median follow up time of 12 years (range 0‐24), 9 patients (22.5%) had disease recurrence; the majority of whom (8 patients), had local recurrence and all were salvaged with total laryngectomy. Eight patients (20%) developed second primaries in the head and neck region with a median time to diagnosis of 77 months (range 8‐227 months). Ten‐years overall survival, disease specific survival, and local disease‐free survival were 80%, 90%, and 80%, respectively. Five patients had postoperative laryngeal dysfunction with a total 10‐years laryngectomy free survival of 70%.

VPL has a sustainable oncologic outcome with a high long‐term laryngectomy free survival rate. This entity is an acceptable conservative salvage option for selected postradiated recurrent laryngeal squamous cell carcinoma patients.

## Linked entities

- **Diseases:** laryngeal squamous cell carcinoma (MONDO:0005595)

## Full-text entities

- **Diseases:** laryngeal squamous cell carcinoma (MESH:D000077195), Laryngeal Cancer (MESH:D007822), local recurrence (MESH:D009364), disease (MESH:D004194), laryngeal dysfunction (MESH:D007818), glottic carcinoma (MESH:C563636)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC11330586/full.md

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Source: https://tomesphere.com/paper/PMC11330586