# Sub-massive Pulmonary Embolism and New-Onset Diabetes Mellitus

**Authors:** Sapna Rama, Ilya Fonarov, Damian Casadesus

PMC · DOI: 10.7759/cureus.64751 · Cureus · 2024-07-17

## TL;DR

A patient with a sub-massive pulmonary embolism was also diagnosed with new-onset diabetes, highlighting the need for integrated care.

## Contribution

This case report highlights the coexistence of sub-massive PE and new-onset diabetes, emphasizing comprehensive patient management.

## Key findings

- The patient was diagnosed with sub-massive PE and new-onset diabetes mellitus.
- Systemic thrombolysis and insulin therapy were used to treat PE and diabetes, respectively.
- The case emphasizes the importance of managing both acute and metabolic conditions simultaneously.

## Abstract

Pulmonary embolism (PE) is a life-threatening disease with variable clinical signs and symptoms, and the diagnosis often requires a high index of suspicion. Patients can have a variety of risk factors that predispose them to venous thromboembolic (VTE) disease. This is a case of a female who presented to the emergency room with new-onset fatigue and shortness of breath for five days. The patient was diagnosed with a sub-massive PE with high-risk features. The patient was also hyperglycemic and diagnosed with new-onset diabetes mellitus. For the PE, she was treated with systemic thrombolysis followed by a standard oral factor Xa inhibitor; for her new onset of diabetes, the patient was started on glargine and lispro insulin. This case underscores the importance of comprehensive management for patients with PE and concurrent metabolic conditions.

## Linked entities

- **Diseases:** pulmonary embolism (MONDO:0005279), diabetes mellitus (MONDO:0005015)

## Full-text entities

- **Diseases:** fatigue (MESH:D005221), PE (MESH:D011655), shortness of breath (MESH:D004417), Diabetes Mellitus (MESH:D003920), venous thromboembolic (VTE) disease (MESH:D054556), hyperglycemic (MESH:D006944)
- **Chemicals:** lispro insulin (MESH:D061268), glargine (MESH:D000069036)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11329189/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11329189/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC11329189/full.md

---
Source: https://tomesphere.com/paper/PMC11329189