# Factors Associated With Non-Uptake of Implantable Cardioverter-Defibrillator (ICD) Among Eligible Patients at a Tertiary Hospital in Kenya

**Authors:** Emmanuel Oluoch, Jasmit Shah, Mohamed Varwani, Mohamed Jeilan, Mzee Ngunga

PMC · DOI: 10.5334/gh.1346 · Global Heart · 2024-08-16

## TL;DR

This study identifies factors linked to low uptake of implantable cardioverter-defibrillators (ICDs) among eligible heart failure patients in Kenya.

## Contribution

The study provides novel insights into ICD non-uptake in Kenya, highlighting insurance status, physician specialty, and cardiomyopathy type as key factors.

## Key findings

- Only 33.5% of eligible patients received an ICD, with lack of private insurance being a major barrier.
- Non-cardiology physicians were more likely to be associated with ICD non-uptake.
- The most common reason for ICD refusal was inability to pay for the device.

## Abstract

Efficacy of Implantable Cardioverter-Defibrillator (ICD) implantation in both primary and secondary prevention of Sudden Cardiac Death (SCD) in at-risk population is well established. ICD implantation rates remain low particularly in Africa with a paucity of data regarding factors associated with non-uptake.

The primary study objective was to determine the factors associated with non-uptake of ICD among heart failure (HF) patients with reduced ejection fraction (EF<35%). Reasons for ICD refusal among eligible patients were reviewed as a secondary objective.

This was a retrospective study among HF patients eligible for ICD implantation evaluated between 2018 to 2020. Comparison between ICD recipient and non-recipient categories was made to establish determinants of non-uptake.

Of 206 eligible patients, only 69 (33.5%) had an ICD. Factors independently associated with non-uptake were lack of private insurance (42.3% vs 63.8%; p = 0.005), non-cardiology physician (16.1% vs 5.8%; p = 0.045) and non-ischemic cardiomyopathy (54.7% vs 36.4% p = 0.014). The most common (75%) reason for ICD refusal was inability to pay for the device.

ICDs are underutilized among eligible HF with reduced EF patients in Kenya. The majority of patients without ICD had no private insurance, had non-ischemic cardiomyopathy and non-cardiology primary physician. Early referral of HF with reduced EF patients to HF specialists to optimize guideline-directed medical therapy and make ICD recommendation is needed.

## Linked entities

- **Diseases:** heart failure (MONDO:0005252), Sudden Cardiac Death (MONDO:0007264), cardiomyopathy (MONDO:0004994)

## Full-text entities

- **Diseases:** HF (MESH:D006333), reduced EF (MESH:D001523), SCD (MESH:D016757), ischemic cardiomyopathy (MESH:D009202)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

25 references — full list in the complete paper: https://tomesphere.com/paper/PMC11328684/full.md

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Source: https://tomesphere.com/paper/PMC11328684