# Total Intravenous Anesthesia Using Remimazolam for Transcarotid Approach Transcatheter Aortic Valve Replacement: A Case Report

**Authors:** Atsuhiro Kitaura, Hiroatsu Sakamoto, Shota Tsukimoto, Haruyuki Yuasa, Yasufumi Nakajima

PMC · DOI: 10.7759/cureus.64628 · Cureus · 2024-07-16

## TL;DR

This case report describes the successful use of remimazolam for anesthesia during a new heart valve procedure, with no major complications.

## Contribution

Demonstrates the feasibility of remimazolam for transcarotid TAVR due to its minimal circulatory impact and rapid recovery.

## Key findings

- The patient experienced no hypotension during anesthesia induction.
- Intraoperative blood pressure was easily controlled.
- Neurological findings were normal after rapid awakening with flumazenil.

## Abstract

The transcarotid approach was introduced in Japan in April 2024 as an alternative approach for transcatheter aortic valve replacement (TAVR). Because carotid artery blood flow is reduced on one side during the procedure, there is a risk of intraoperative brain stroke. Therefore, it is crucial to check for cerebral complications immediately after the procedure. We report a case involving an 87-year-old female who underwent transcarotid TAVR under general anesthesia with remimazolam and remifentanil. The operation was completed in a short period. There was no evidence of hypotension during the induction of anesthesia, and intraoperative blood pressure control was easy. However, there was a decrease in local oxygen saturation for approximately nine minutes intraoperatively. Following the administration of flumazenil, the patient was quickly awakened, and neurological findings were confirmed to be normal. The patient was discharged without complications. Our findings suggest that remimazolam, an ultra-short-acting benzodiazepine, is feasible for the transcarotid TAVR procedure due to its minimal circulatory impact and ability to facilitate rapid and reliable arousal.

## Linked entities

- **Chemicals:** remimazolam (PubChem CID 9867812), remifentanil (PubChem CID 60815), flumazenil (PubChem CID 3373)

## Full-text entities

- **Diseases:** cerebral complications (MESH:D008107), hypotension (MESH:D007022), stroke (MESH:D020521)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11326771/full.md

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11326771/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC11326771/full.md

---
Source: https://tomesphere.com/paper/PMC11326771