# Metastatic Pure Choriocarcinoma Masquerading in the Gastrointestinal Tract

**Authors:** Parvir Aujla, Abdullah S Aleem, Rohit Khanna, Nitish Mittal, John Lyons

PMC · DOI: 10.7759/cureus.64566 · Cureus · 2024-07-15

## TL;DR

A rare case of pure choriocarcinoma metastasizing to the gastrointestinal tract is reported in a patient previously in remission.

## Contribution

This case highlights the potential for metastatic PCC to affect the gastrointestinal tract despite prior remission.

## Key findings

- A 52-year-old male with a history of mixed germ cell tumor in remission developed metastatic PCC in the gastrointestinal tract.
- Endoscopic and CT-guided biopsy confirmed metastatic PCC despite prior negative surveillance.
- The case underscores the aggressive nature of PCC and the need for vigilance in atypical presentations.

## Abstract

This study presents a rare case of pure choriocarcinoma (PCC) with metastasis to the gastrointestinal tract in a 52-year-old male with a history of mixed germ cell tumor in remission. Despite negative oncology surveillance imaging, serum marker monitoring, and a recent colonoscopy, the patient presented with new-onset melena and dysphagia, leading to further diagnostic evaluation. Endoscopic examination revealed an ulcerated duodenal mass, and a computer tomography (CT)-guided liver biopsy confirmed metastatic PCC. This case highlights the aggressive nature of PCC and the importance of considering gastrointestinal metastasis in patients with atypical symptoms, even when in apparent remission.

## Linked entities

- **Diseases:** choriocarcinoma (MONDO:0003508), mixed germ cell tumor (MONDO:0003120)

## Full-text entities

- **Diseases:** germ cell tumor (MESH:D009373), mass (MESH:C536030), dysphagia (MESH:D003680), PCC (MESH:D002822), gastrointestinal metastasis (MESH:D009362), metastasis to the gastrointestinal tract (MESH:D005770), melena (MESH:D008551)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11323720/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC11323720/full.md

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Source: https://tomesphere.com/paper/PMC11323720