# Airway management of a patient with coffin-lowry syndrome: a case report

**Authors:** Shaarav Ghose, Faria Nisar, Bushra Abdul Aleem

PMC · DOI: 10.1186/s12871-024-02667-7 · BMC Anesthesiology · 2024-08-14

## TL;DR

This case report details the challenges of managing anesthesia for a patient with Coffin-Lowry Syndrome, a rare genetic disorder.

## Contribution

The paper provides a detailed account of anesthetic management for a rare genetic condition, offering insights to improve clinical care.

## Key findings

- Anesthetic management of Coffin-Lowry Syndrome requires careful perioperative considerations.
- Difficult airway management is a significant challenge in patients with CLS.

## Abstract

Coffin-Lowry Syndrome (CLS) is a rare X-linked genetic disorder characterized by growth delays, facial dysmorphisms, and intellectual disabilities. Currently, there are limited published case reports regarding the anesthetic management of patients with CLS. Managing anesthesia for CLS patients can be complex due to difficult airway management. In this case report, we present a patient with CLS who underwent surgical intervention, highlighting the anesthetic considerations encountered throughout the perioperative period. We aim to summarize the difficulties involved in anesthetic management of rare conditions like CLS to improve clinical outcomes for affected individuals.

## Linked entities

- **Diseases:** Coffin-Lowry Syndrome (MONDO:0010561)

## Full-text entities

- **Diseases:** intellectual disabilities (MESH:D008607), growth delays (MESH:D006130), X-linked genetic disorder (MESH:D040181), CLS (MESH:D038921), facial dysmorphisms (MESH:C565579)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11323679/full.md

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Source: https://tomesphere.com/paper/PMC11323679