# A Case Report of Tranexamic Acid for the Treatment of Chronic Subdural Hematoma in an 86-Year-Old Patient

**Authors:** Shatha Gharaibeh, Abdallah Shurman, Abeer Gharaibeh, Roy Torcuator

PMC · DOI: 10.7759/cureus.66846 · Cureus · 2024-08-14

## TL;DR

This case report shows that tranexamic acid can effectively treat chronic subdural hematoma in an elderly patient, avoiding surgery.

## Contribution

Demonstrates tranexamic acid's efficacy in treating CSDH in an elderly patient with comorbidities, avoiding surgical intervention.

## Key findings

- Tranexamic acid led to complete resolution of the hematoma in an 86-year-old patient.
- No recurrence was observed during two years of follow-up.
- The treatment may serve as a non-surgical alternative for CSDH.

## Abstract

Fibrinolytic and coagulative hyperactivity is proven to have a role in liquefaction and progression of chronic subdural hematoma (CSDH). Tranexamic acid was one of the pharmaceutical options that was explored, as it inhibits the hyper-fibrinolytic activity and reduces the vascular permeability in CSDH, leading to a gradual resolution of the hematoma. In this case study, we present a case of using tranexamic acid for CSDH treatment in an 86-year-old patient with co-morbidities. The complete resolution of the hematoma following using tranexamic acid in this case with no history of recurrence in two years follow-up supports its efficacy in CSDH treatment and may be considered as one of the strategies that help prevent surgeries.

## Linked entities

- **Chemicals:** Tranexamic acid (PubChem CID 5526)

## Full-text entities

- **Diseases:** CSDH (MESH:D020200), hematoma (MESH:D006406)
- **Chemicals:** Tranexamic Acid (MESH:D014148)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

28 references — full list in the complete paper: https://tomesphere.com/paper/PMC11323430/full.md

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Source: https://tomesphere.com/paper/PMC11323430