# Beyond the Splanchnic Area: Extra-splanchnic Thrombosis in Acute Pancreatitis

**Authors:** Varsha Shinde, Pranay Penmetsa, Yash Dixit

PMC · DOI: 10.7759/cureus.64555 · Cureus · 2024-07-15

## TL;DR

This paper discusses rare extra-splanchnic venous thrombosis in acute pancreatitis and highlights the need for better understanding and treatment.

## Contribution

The paper presents a case report emphasizing the rarity and under-researched nature of extra-splanchnic thrombosis in acute pancreatitis.

## Key findings

- Extra-splanchnic venous thrombosis is a rare complication of acute pancreatitis.
- Thrombosis formation involves pancreatic inflammation and immune response.
- There is limited literature on treating these thromboses with anticoagulation.

## Abstract

Acute pancreatitis (AP) is an inflammatory condition with varied clinical presentations. Local complications include peripancreatic fluid collection, acute necrotic collection, walled-off necrosis, and pancreatic pseudocyst, but vascular complications like pseudoaneurysm and venous thrombosis are also reported. Patients often experience splanchnic venous thrombosis, which can affect the splenic vein, portal vein, and superior mesenteric vein individually or in combination. Rarely, extra-splanchnic venous thrombosis, including renal vein, superior vena cava, and inferior vena cava thrombosis, has been reported in cases of chronic pancreatitis. The formation of a venous thrombus in acute pancreatitis is multifaceted, with pancreatic inflammation and the immune response mounted by the patient playing a significant role. There is a dearth of medical literature regarding extra-splanchnic venous thrombosis and the use of therapeutic anticoagulation in the successful treatment of the above-mentioned complication. This case report highlights the rare complications that can be seen in cases of acute pancreatitis.

## Linked entities

- **Diseases:** acute pancreatitis (MONDO:0006515)

## Full-text entities

- **Diseases:** venous thrombosis (MESH:D020246), renal vein (MESH:D059228), vena cava (MESH:D013479), inferior vena cava thrombosis (MESH:C563013), pancreatic pseudocyst (MESH:D010192), chronic pancreatitis (MESH:D050500), AP (MESH:D010195), necrosis (MESH:D009336), complications (MESH:D008107), inflammatory (MESH:D007249), pseudoaneurysm (MESH:D017541), Thrombosis (MESH:D013927)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11322905/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC11322905/full.md

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Source: https://tomesphere.com/paper/PMC11322905