# Multiple adenomas of the thyroid gland in an African green monkey (Chlorocebus aethiops)

**Authors:** Roland Plesker, Kernt Köhler

PMC · DOI: 10.5194/pb-10-1-2023 · Primate Biology · 2023-05-12

## TL;DR

An African green monkey had three thyroid tumors, two of which were cystadenomas and one a solid adenoma, with distinct characteristics observed through histology and immunostaining.

## Contribution

The study reports and characterizes multiple thyroid adenomas in an African green monkey, providing a rare pathological case study.

## Key findings

- The solid adenoma was a well-defined microfollicular follicular adenoma positive for thyroglobulin.
- The cystadenomas were positive for both thyroglobulin and calcitonin.
- No evidence of hormone overproduction was associated with the tumors.

## Abstract

Two cystadenomas and one solid adenoma of the thyroid gland in a 27-year-old female African green monkey (Chlorocebus aethiops) are described here. Histologically, the solid
adenoma was classified as a well-defined solid follicular adenoma of
microfollicular type. The solid adenoma was positive for thyroglobulin in
immunohistochemistry staining, whereas the cystadenomas stained positive for both thyroglobulin and calcitonin. No evidence of excess hormone production related to the tumor presence was detected.

## Linked entities

- **Proteins:** Calca (calcitonin-related polypeptide alpha)
- **Species:** Chlorocebus aethiops (taxon 9534)

## Full-text entities

- **Diseases:** cystadenomas (MESH:D003537), tumor (MESH:D009369), adenoma of the thyroid gland (MESH:D013964), adenoma (MESH:D000236)
- **Species:** Chlorocebus aethiops (African green monkey, species) [taxon 9534]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11322656/full.md

## References

36 references — full list in the complete paper: https://tomesphere.com/paper/PMC11322656/full.md

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Source: https://tomesphere.com/paper/PMC11322656