# Peripheral giant cell granuloma in a child with ectrodactyly-ectodermal dysplasia-cleft lip/palate syndrome: a case report

## TL;DR

A child with EEC syndrome developed a peripheral giant cell granuloma in the mouth, which was successfully treated with surgery and showed no recurrence over two years.

## Contribution

This case report adds to the limited literature on oral manifestations of EEC syndrome and emphasizes dental involvement in its management.

## Key findings

- A peripheral giant cell granuloma was identified in a child with EEC syndrome.
- Surgical excision under local anesthesia resolved the lesion with no recurrence over 24 months.
- Dentists play a key role in managing oral conditions associated with EEC syndrome.

## Abstract

Ectrodactyly-ectodermal dysplasia-cleft lip/palate (EEC) syndrome mainly affects ectodermal and mesodermal tissues. It is usually manifested as split hands and feet, ectodermal dysplasia, and orofacial clefting, along with other signs and symptoms. A multidisciplinary approach to treatment is required, in which dentists play an important role in identifying and treating various oral conditions that may be genetically linked to or may be the result of EEC syndrome.

The present case describes the oral condition of a young child suffering from EEC syndrome and presenting with peripheral giant cell granuloma (PGCG) in the mandibular anterior region. After obtaining a thorough medical and family history and a clinical examination, the lesion was surgically excised under local anesthesia. The patient was followed up at periodic intervals for the next twenty four months, during which no recurrence of the lesion was observed.

This report highlights the role of a dentist in the management of the oral conditions of patients suffering from EEC syndrome.