# Pilomatricoma in the infraorbital region

## TL;DR

This case study presents a rare benign skin tumor called pilomatricoma located in the infraorbital region of a 32-year-old male.

## Contribution

The novelty lies in presenting a specific case of pilomatricoma in the infraorbital region, emphasizing its diagnostic and clinical relevance.

## Key findings

- Pilomatricoma typically presents as a painless, firm lesion and is more common in females.
- Histopathological analysis reveals basaloid cells and shadow cells as characteristic features.
- Complete surgical excision is the recommended treatment to prevent recurrence.

## Abstract

Pilomatricoma, a rare benign skin tumor arising from hair follicle matrix cells, warrants consideration in the evaluation of subcutaneous nodules or masses, especially when presenting as painless and firm lesions. Accurate diagnosis hinges on histopathological examination, underscoring the significance of clinician vigilance and prompt intervention.

Pilomatricoma, also referred to as Pilomatrixomas or Calcifying epithelioma of Malherbe, is a rare benign skin tumor derived from hair follicle matrix cells, presents a diagnostic challenge due to its diverse clinical manifestations. Females are more commonly affected by Pilomatricoma. This condition typically manifests as a painless, firm, and slowly progressive lesion. Histopathological analysis shows characteristic findings, such as basaloid cells at the periphery and shadow cells centrally. Immunohistochemical studies assess the expression of cytokeratin's associated with hair matrix differentiation. Complete surgical excision remains the cornerstone of treatment, ensuring favorable outcomes and minimizing the risk of recurrence. Awareness of this entity among clinicians is essential for timely recognition and appropriate intervention. In this specific case‐study, we present a case of Pilomatricoma situated in the lower left orbital region of a 32‐year‐old male individual who had been noticing swelling in that vicinity over the preceding 7 months.