The improvement of fibrinogen, Ang-1, VEGF, BDNF in post-operative patients with brain trauma through target task-oriented phase training

TL;DR

This study examines how target task-oriented training affects recovery markers and quality of life in brain trauma patients after surgery.

Contribution

The novel contribution is evaluating the impact of target task-oriented training on specific biomarkers and functional recovery in post-operative brain trauma patients.

Findings

Target task-oriented training improved fibrinogen, Ang-1, VEGF, and BDNF levels in post-operative brain trauma patients.

Patients receiving target task-oriented training showed better limb function and quality of life improvements over time.

The experimental group demonstrated significant recovery compared to routine training at multiple time points.

Abstract

It aims to explore the effect of target task-oriented phase training on fibrinogen (Fbg), angiopoietin (Ang-1), vascular endothelial growth factor (VEGF), serum brain-derived neurotrophic factor (BDNF), and quality of life in post-operative patients with brain trauma.

142 patients with brain trauma who were operated on in neurosurgery of our hospital from March 2020 to March 2023 were chosen and separated into two groups by random number table. The control group (n=71) received routine post-operative training. The experimental group (n=71) received target task-oriented training based on the control group, and the serum cell levels of nursing for 3, 7, and 14 days were compared. Improvement of limb function and quality of life after 2, 4, and 6 weeks of nursing care is observed.

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