Attachment Gain After Applying Xenogeneic Acellular Dermal Matrix in the Management of Isolated Recessions: A Randomized Clinical Trial

TL;DR

This study compares two surgical techniques for treating gum recession and finds that one provides better results in regenerating gum tissue.

Contribution

The study introduces a comparison of Xenogeneic Acellular Dermal Matrix and connective tissue grafts in mucogingival surgery.

Findings

Both graft types led to attachment gain, but the connective tissue graft showed greater improvement.

After six months, the CTG+CAF group had a mean relative attachment level of 8.333±0.899.

The XDM+CAF group had a mean relative attachment level of 8.466±0.833 after six months.

Abstract

Background and objectives

Mucogingival plastic surgery is a surgical procedure performed to prevent or correct anatomical, developmental, or traumatic defects. The problem of gingival recession is common in dental practice, causing pain and dentin hypersensitivity for the patient, and remains difficult to treat surgically at the second surgical site used to harvest the connective graft. Many alternatives have been used to replace connective grafts, but none have been as effective. The importance of guided tissue regeneration remains to gain attachment because it means the formation of new periodontal tissue. This study aims to evaluate the attachment gain (AG) obtained after the management of single gingival recessions of Class I and Class II of Miller's classification.

Material and methods

This study was designed as a clinical randomized trial using a split-mouth technique. The study sample included 15 patients (30 symmetrical gingival recessions). The first group included the coronally advanced flap (CAF) with the connective tissue graft (CTG), and the second group included the CAF with the Xenogeneic Acellular Dermal Matrix (XDM) (Mucoderm®, Botiss Biomaterials, Zossen, Germany). AG was measured at baseline and after six months.

Results

The results showed that the mean relative attachment level at baseline was 8.333±0.899 in the CTG+CAF group and 8.466±0.833 in the XDM+CAF group. After six months of follow-up, the levels remained 8.333±0.899 in the CTG+CAF group and 8.466±0.833 in the XDM+CAF group, with a significant difference between the study groups after six months.

Conclusion

The current study concluded that both grafts applied with the coronally advanced flap led to a gain in attachment, with a greater gain in the CTG group.

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