# Caudiquinol: A Meroterpenoid with an Intact C20 Geranylgeranyl Chain Isolated from Garcinia caudiculata

## TL;DR

Researchers discovered a new natural compound, caudiquinol, from Garcinia caudiculata, which contains an intact geranylgeranyl chain, a rare feature in plant compounds.

## Contribution

The study reports the isolation and characterization of a new meroterpenoid, caudiquinol, from Garcinia caudiculata.

## Key findings

- A new hydroquinone methyl ester, caudiquinol, was isolated and identified from Garcinia caudiculata.
- Caudiquinol and another known compound were found to have an intact C20 geranylgeranyl chain.
- This is the first phytochemical investigation of Garcinia caudiculata from Borneo.

## Abstract

The tropical Garcinia genus of flowering plants is a prolific producer of aromatic natural products including polyphenols, flavonoids, and xanthones. In this study, we report the first phytochemical investigation of Garcinia caudiculata Ridl. from the island of Borneo. Fractionation, purification, and structure elucidation by MS and NMR resulted in the discovery of two meroterpenoids. One was a benzofuranone lactone previously isolated from Iryanthera grandis and Rhus chinensis, and the second was a new hydroquinone methyl ester that we named caudiquinol. Both natural products are rare examples of plant meroterpenoids with an intact geranylgeranyl chain.