# Pre and post-operative serum levels of titanium cobalt and aluminium after implant placement

**Authors:** Richa Jain, Bhumika Sehdev, Pratik Chaudhari, Sanjukta Panda, Binoo Verma, Supriya Mishra, Mahesh Ghadage, Miral Mehta

PMC · DOI: 10.6026/973206300200690 · Bioinformation · 2024-06-30

## TL;DR

This study found that dental implants do not significantly increase metal ion levels in the blood, suggesting no toxicity risk.

## Contribution

The study provides new evidence on the safety of dental implants regarding metal ion release.

## Key findings

- Serum levels of titanium, cobalt, and aluminium increased slightly after 12 months of implant placement.
- The observed increase in metal ion levels was not statistically significant.
- Dental implants do not pose a toxicity risk due to minimal metal ion release.

## Abstract

The preoperative serum levels and postoperative serum levels of titanium, cobalt and aluminium from dental implants in order to
assess the release of these ions and to assess any risk of toxicity from these ions after dental implant placement is of interest to
dentists. It was observed that there was very slight increase in serum concentration of titanium, cobalt and aluminium after 12 months
of placement of implants as compared to before placement of implants. However the increase was non-significant statistically. Our study
concluded that the use of dental implants does not pose any risk of toxicity of metal ions like titanium, aluminium and cobalt because
of very slight non-significant increase in serum levels of these ions 12 months after implant placement.

## Linked entities

- **Chemicals:** titanium (PubChem CID 23963), cobalt (PubChem CID 104730), aluminium (PubChem CID 5359268)

## Full-text entities

- **Diseases:** toxicity (MESH:D064420)
- **Chemicals:** titanium (MESH:D014025), cobalt (MESH:D003035), aluminium (MESH:D000535), titanium cobalt (-)

## Full text

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## References

26 references — full list in the complete paper: https://tomesphere.com/paper/PMC11312326/full.md

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Source: https://tomesphere.com/paper/PMC11312326