# Analysis of salivary alpha-L-fucosidase and salic acid among oral sub-mucous fibrosis patients

## TL;DR

This study compares salivary alpha-L-fucosidase and salic acid levels in oral submucous fibrosis patients and healthy individuals to identify potential biomarkers for diagnosis.

## Contribution

The study identifies salivary alpha-L-fucosidase and salic acid as potential biomarkers for diagnosing oral submucous fibrosis.

## Key findings

- Salivary and serum alpha-L-fucosidase levels were higher in OSMF patients compared to controls.
- Salivary and serum salic acid levels were significantly elevated in OSMF patients.
- Salivary biomarkers may aid in the early diagnosis of oral submucous fibrosis.

## Abstract

The salivary concentrations of alpha L fucosidase (AFU) and salic acid (SA) in oral submucous fibrosis patients and compare it with
healthy controls is of interest to dentists. 40 patients of OSMF and 40 healthy controls were included. Estimation of AFU and SA in
saliva and serum was carried out in every patient. The serum level of AFU was 37.4±26.8 in OSMF patients and saliva level of AFU was
35.4±14.5. The serum level of AFU was 19.2±4.3 in control group and saliva level of AFU was 35.4±14.5 in control group. The serum level
of SA was 20.32±2.71 in OSMF patients and saliva level of SA was 18.21±2.40. The serum level of SA was 4.89 ±1.17 in control group and
saliva level of SA was 3.13 ±1.04 in control group. Estimation of concentration of SA and AFU in saliva can be effective biomarker in
diagnosis of OSMF.