# Post-COVID-19 Condition: How Sociodemographic Factors, Physical Well-Being and Functionality Influence Quality of Life and Mental Health Symptoms

**Authors:** Mᵃ Pilar Rodríguez-Pérez, Marta Pérez-de-Heredia-Torres, Pilar Rodríguez-Ledo, Gemma Fernández-Gómez, Cristina García-Bravo, Roberto Cano-de-la-Cuerda, Patricia Sánchez-Herrera-Baeza

PMC · DOI: 10.3390/healthcare12151551 · Healthcare · 2024-08-05

## TL;DR

The study explores how sociodemographic factors and physical health affect mental health and quality of life in people with long COVID.

## Contribution

The study identifies specific sociodemographic and clinical variables that influence mental health symptoms in post-COVID-19 patients.

## Key findings

- Older age, gender, and longer illness duration are linked to higher mental health symptoms in post-COVID-19 patients.
- Better physical functioning and independence reduce the risk of mental health symptoms in these patients.
- Variables like age, physical functioning, and disease duration show significant associations with asthenia, low mood, and anxiety.

## Abstract

Background: Long COVID-19 syndrome remains a global public health problem, with more than 145 million people affected with multisystemic symptoms. Addressing the requirements of individuals impacted by a syndrome characterised by a complex and variable clinical presentation is of utmost importance. Identifying the variables that can exert influence and understanding their progression is essential for directing treatment strategies aimed at enhancing both independence and quality of life. Therefore, the aim of this study was to analyse the influence of sociodemographic and clinical variables on existence and their relationship with asthenia, anxiety symptoms and low mood. Methods: An analytical study secondary to an observational cross-sectional descriptive study. Results: Logistic regression showed significant univariate effects on asthenia [sex (p = 0.034); age (p = 0.042); Activities of Daily Living Questionnaire [ADQL (p = 0.002)] [physical functioning (p < 0.001) and general health (p = 0.014)] and multivariate [sex (p = 0.019), adult age (p = 0.01) and physical functioning (p = 0.04)]]; low mood [time of evolution (p = 0.028) and multivariate [time course (p = 0.007), ADLQ (p = 0.011), role physical (p = 0.013) and general health (p = 0.001)]] and anxiety [physical functioning (p = 0.046) and multivariate [physical functioning (p = 0.034), age (p = 0.011), time of evolution (p = 0.001) and ADQL (p = 0.011)]]. Conclusions: Increased age, gender and longer evolution time seem to favour the prevalence and occurrence of mental health symptoms; greater independence and good physical functioning are protective factors with respect to the occurrence of mental health-related symptoms in patients affected by post-COVID-19 condition.

## Full-text entities

- **Diseases:** low mood (MESH:D019964), Long COVID-19 syndrome (MESH:D000094024), anxiety symptoms (MESH:D001008), Mental Health Symptoms (OMIM:603663), anxiety (MESH:D001007), asthenia (MESH:D001247)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

36 references — full list in the complete paper: https://tomesphere.com/paper/PMC11312060/full.md

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Source: https://tomesphere.com/paper/PMC11312060