Correction: Positive Feedback-Loop of Telomerase Reverse Transcriptase and 15-Lipoxygenase-2 Promotes Pulmonary Hypertension
Tingting Shen, Jun Ma, Lei Zhang, Xiufeng Yu, Mengmeng Liu, Yunlong Hou, Yanyan Wang, Cui Ma, Shuzhen Li, Daling Zhu
Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsPulmonary Hypertension Research and Treatments · Eicosanoids and Hypertension Pharmacology · Sulfur Compounds in Biology
After publication of this article [1], concerns were raised about Fig 2. Specifically, in Fig 2A, the Control and MCT+AZT panels appear to show the same field of view.
The first and corresponding authors stated that this duplication was the result of a figure preparation error. An updated version of Fig 2 is provided here in which the images have been corrected.
The replacement images provided for Fig 2 show demonstrably less purple staining than the originally published panels. The authors clarified that, during preparation of the original images, they had adjusted the saturation with the intention of making the brown stain more visible. In the updated Fig 2, they have presented the original, unadjusted images.
During editorial follow-up, additional concerns were raised regarding the cytological quantification of TERT. In response, the first and corresponding authors provided the following explanations:
Underlying image data supporting Fig 2A are available in S1 File. The original individual-level quantitative data from which Fig 2B was generated are available in S2 File.
A member of the PLOS ONE Editorial Board reviewed the updated Fig 2, the underlying data, and the additional methodological details provided by the authors, and was satisfied that the raw data support the published results.
The authors apologize for the errors in the published article.
Supporting information
S1 FileUnderlying image data supporting Fig 2A.(ZIP)
S2 FileIndividual-level quantitative data supporting Fig 2B.(XLSX)
The reference list from the paper itself. Each links out to its DOI / PubMed record.