# Age dependent vestibulo-ocular reflex gain in video head impulse test among normal Indians

**Authors:** Saraswathi Avula, Saran Kumar, Senthi Vadivu, Mohan Kameswaran

PMC · DOI: 10.6026/973206300200520 · Bioinformation · 2024-05-31

## TL;DR

This study examines how age affects the vestibulo-ocular reflex in healthy Indians using a video head impulse test.

## Contribution

The study provides normative data on VOR gain across age groups in the Indian population.

## Key findings

- VOR gain was not significantly affected by age in the studied population.
- No overt saccades were observed, and covert saccades were insignificant.
- Normative VOR gain values can help identify vestibular loss in patients with dizziness.

## Abstract

Determination of the normative data of Vestibulo-Ocular Reflex gain using VHIT of all three semicircular canals (anterior, posterior,
horizontal) on both sides in different age groups is of interest. This is an observational study comprised of 10 healthy individuals in
each decade from less than 10 years to 80 years of both sexes making a total of 80. The study was done using the equipment SYNAPSYS VHIT
ULMER with Software EVOLUTION 3.0. Mean VOR gain of each decade for all the semicircular canals is calculated and they are compared using
ANOVA (Analysis of variance). In our study, percentage of patients with overt saccades is nil. Hence, in our study, the occurrence of
covert saccades was insignificant as compared to the above studies. Age dependent VOR gain in normal individuals did not have any
significance in our study of 80 patients performed by video head impulse test. VOR gain in our study is not affected by age. Normative
data for different age groups obtained compared among different age groups showing no significant difference in Mean VOR gain. The
normative values of VOR gain can be compared to patients with dizziness thus helping in determining any vestibular loss.

## Full-text entities

- **Diseases:** dizziness (MESH:D004244), vestibular loss (MESH:D000071699)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC11309093/full.md

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Source: https://tomesphere.com/paper/PMC11309093