# Familial Spontaneous Keloids: Examining Thoracic Manifestations in Two Brothers

## TL;DR

This paper reports a rare case of spontaneous keloids in two brothers' chest area, showing possible genetic factors and their response to treatment.

## Contribution

The study presents a novel case of familial spontaneous keloids without trauma history, emphasizing genetic predisposition.

## Key findings

- Two brothers developed spontaneous keloids on their thoracic region with no prior trauma.
- The keloids responded to triamcinolone treatment over several years.
- The case suggests a possible genetic basis for spontaneous keloid formation.

## Abstract

Keloids are complex fibroproliferative disorders with diverse clinical presentations. Spontaneous keloids (SKs) represent a rare subtype that emerges without any known preceding traumatic event. This report presents a case of familial spontaneous keloids appearing on the thoracic region in two brothers with no prior history of trauma or keloid occurrence in other family members. The lesions exhibited progressive growth over several years but responded to cycles of triamcinolone treatment. This case underscores an unusual spontaneous occurrence of keloids in the thoracic region of two siblings, highlighting the potential genetic predisposition in the aetiology of these lesions. Additionally, this instance reinforces the concept that keloids can develop spontaneously without any apparent trauma in the affected area.