# Beneath the Surface: A Case Report Revealing a Rare Cystic Neoplasm Hidden Within a Pseudocyst in the Pancreas and a Scientific Literature Review

## TL;DR

A rare pancreatic tumor was found inside a pseudocyst, highlighting the challenges in diagnosing and treating such cases.

## Contribution

This case report adds to the limited literature on SPNs by describing a unique presentation within a pseudocyst.

## Key findings

- The patient had a large cystic neoplasm involving the entire pancreas.
- Total pancreatectomy with duodenectomy was performed due to the extensive lesion.
- Histopathology confirmed the diagnosis of solid pseudopapillary neoplasm.

## Abstract

Solid pseudopapillary neoplasms (SPNs) of the pancreas are rare tumours with distinctive clinicopathological features. We present a case of a 51-year-old female with a large cystic neoplasm involving the entire pancreas, initially presenting with abdominal pain. Diagnostic imaging revealed a well-defined heterogeneously enhancing mixed solid cystic lesion in the pancreas. Surgical exploration confirmed a lesion in the entire pancreas, prompting total pancreatectomy with duodenectomy. Postoperative histopathology and immunohistochemistry supported the diagnosis of SPN. Herein, we discuss SPN's clinical presentation, diagnostic challenges, surgical management, and pathological characteristics.