# A Case of Recurrence of Fibrolamellar Hepatocellular Carcinoma After 18 Years Underscores the Need for Extended Patient Surveillance

## TL;DR

A patient with a rare liver cancer had a recurrence 18 years after surgery, suggesting the need for long-term monitoring.

## Contribution

Highlights the importance of extended surveillance for fibrolamellar hepatocellular carcinoma survivors.

## Key findings

- FLC can recur nearly two decades after curative surgery.
- Long-term imaging surveillance is recommended for FLC patients.
- Current guidelines lack clarity on optimal surveillance duration.

## Abstract

Fibrolamellar hepatocellular carcinoma (FLC) is a rare form of primary liver cancer that predominantly affects adolescents and young adults with no history of cirrhosis. Surgical resection is a potentially curative treatment option, but the optimal duration of surveillance after a potentially curative surgical resection is not known. Here, we present a case of a patient with FLC who developed a recurrence of FLC nearly two decades after resection of the primary tumor. Although the optimal duration of imaging surveillance for FLC is not known, this case report provides initial evidence that long-term surveillance in patients with FLC who have received curative intent surgery is warranted.