# Assessment of the feed additive consisting of endo‐1,4‐beta‐xylanase (produced with Trichoderma reesei MUCL 49755) and endo‐1,3(4)‐beta‐glucanase (produced with T. reesei MUCL 49754) (AveMix® XG 10) for pigs for fattening, minor porcine species for fattening and turkeys for fattening for the renewal of its authorisation (AVEVE BV)

**Authors:** Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Ilen Röhe, Katerina Theodoridou, Montserrat Anguita, Matteo Lorenzo Innocenti, Jordi Tarrés‐Call, Elisa Pettenati

PMC · DOI: 10.2903/j.efsa.2024.8951 · EFSA Journal · 2024-08-08

## TL;DR

This paper assesses the safety of a feed additive for fattening pigs and turkeys, confirming it is safe for animals, consumers, and the environment.

## Contribution

The study confirms the safety of a modified feed additive formulation for use in animal feed.

## Key findings

- Both forms of the additive remain safe for pigs, minor porcine species, and turkeys.
- The additive is a respiratory and skin sensitiser but not irritating to skin and eyes.
- No data were provided for one formulation, so its compliance could not be confirmed.

## Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the feed additive consisting of endo‐1,4‐beta‐xylanase (produced with Trichoderma reesei MUCL 49755) and endo‐1,3(4)‐beta‐glucanase (produced with T. reesei MUCL 49754) (AveMix® XG 10/AveMix® XG 10 L) for the renewal of its authorisation as zootechnical feed additive for pigs for fattening, minor porcine species for fattening and turkeys for fattening. The applicant declared a change in the carrier material used in AveMix® XG 10 from soybean meal to calcium carbonate + wheat flour or calcium carbonate + sepiolite. The applicant provided evidence that the additive Avemix® XG 10 with calcium carbonate + wheat flour and Avemix® XG 10 L comply with the conditions of the authorisation. The EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) noted that no data were submitted to support compliance of the formulation of Avemix® XG 10 with calcium carbonate + sepiolite with the conditions of the authorisation. The FEEDAP Panel concluded that both forms of the additive remain safe for pigs for fattening, minor porcine species for fattening and turkeys for fattening, consumers and the environment. Regarding the safety for the user, Avemix® XG 10 formulated with calcium carbonate + sepiolite and Avemix® XG 10 L are not irritant to skin and eyes. No conclusions on the irritation potential of Avemix® XG 10 formulated with calcium carbonate + wheat flour could be drawn. The additive in all its formulations is considered a respiratory and skin sensitiser. There was no need for assessing the efficacy of the additive in the context of the renewal of the authorisation.

## Full-text entities

- **Chemicals:** calcium carbonate (MESH:D002119), AveMix  XG 10 (-)
- **Species:** Sus scrofa (pig, species) [taxon 9823], Meleagris gallopavo (common turkey, species) [taxon 9103], Trichoderma reesei (species) [taxon 51453]

## Full text

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC11306973/full.md

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Source: https://tomesphere.com/paper/PMC11306973