# Small Intestinal Complications of Intestinal Transplant-Associated Microangiopathy Post-stem Cell Transplantation

**Authors:** Daisuke Kametaka, Masaya Iwamuro, Takehiro Tanaka, Ken-ichi Matsuoka, Motoyuki Otsuka

PMC · DOI: 10.7759/cureus.64111 · Cureus · 2024-07-08

## TL;DR

This paper reports a rare case of intestinal complications following a stem cell transplant, highlighting new insights into managing similar patients.

## Contribution

The first report presenting images of possible small intestinal lesions in intestinal transplant-associated microangiopathy.

## Key findings

- A patient developed intestinal transplant-associated microangiopathy (iTAM) seven weeks post-transplantation.
- Video capsule enteroscopy revealed multiple erosions and shallow ulcers in the jejunum and ileum.
- The presented images may aid in managing patients with similar conditions.

## Abstract

We present the case of a patient who underwent human leukocyte antigen-haploidentical transplantation for T-cell acute lymphoblastic leukemia. Seven weeks after transplantation, the patient developed intestinal transplant-associated microangiopathy (iTAM). Although the iTAM was resolved temporarily, it recurred. Video capsule enteroscopy revealed multiple erosions and shallow ulcers in the jejunum and ileum. To the best of our knowledge, this is the first report to present images of possible small intestinal lesions in iTAM. The small intestinal mucosal images presented herein may potentially aid in the management of similar patients.

## Linked entities

- **Diseases:** T-cell acute lymphoblastic leukemia (MONDO:0004963)

## Full-text entities

- **Diseases:** Intestinal Transplant-Associated Microangiopathy (MESH:D007410), ulcers (MESH:D014456), Complications (MESH:D008107), erosions (MESH:D014077), T-cell acute lymphoblastic leukemia (MESH:D054218)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11305607/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC11305607/full.md

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Source: https://tomesphere.com/paper/PMC11305607