# Multiple myeloma in a young female presenting as an aggressive skull-base tumour

## TL;DR

A 21-year-old woman presented with an aggressive skull-base tumor caused by multiple myeloma, a rare occurrence in young individuals.

## Contribution

This case highlights the rare presentation of multiple myeloma as an aggressive skull-base tumor in a young female.

## Key findings

- The patient had a head and neck plasmacytoma confirmed by imaging.
- PET-CT and histology supported the diagnosis of multiple myeloma.
- Lytic bone lesions were identified, indicating systemic disease progression.

## Abstract

Plasma cell neoplasia has a wide presentation of disease (localised or systemic) according to the International Myeloma Working Group. Radiological imaging identifies plasmacytomas as solitary lesions or part of multiple myeloma. We present a rare case of a 21-year-old female who presented with a skull-base tumour.

A head and neck plasmacytoma with further lytic bone lesions was confirmed on imaging. This article presents and discusses the clinical, CT, MRI, positron emission tomography (PET)-CT, histology and laboratory findings.