# Clinicopathological Study of Fibroepithelial Lesions of the Breast in a Tertiary Care Hospital in South India

## TL;DR

This study analyzed breast fibroepithelial lesions in a South Indian hospital to understand their types, age distribution, and tumor size patterns.

## Contribution

The study provides a detailed clinicopathological analysis of fibroepithelial lesions in a South Indian population over an 8-year period.

## Key findings

- 95% of the lesions were fibroadenomas, 3.5% were phyllodes tumors, and 1.5% were fibroadenomas with tubular adenoma.
- The most common age group affected was 21 to 40 years, and phyllodes tumors were typically larger than 5 cm.
- No statistically significant association was found between age, tumor size, and histological grade.

## Abstract

Introduction

Fibroepithelial lesions of the breast mainly include fibroadenoma and phyllodes tumors with overlapping morphological features and varied clinical behavior. This study aims to determine the histopathological spectrum of fibroepithelial lesions of the breast in a tertiary care hospital.

Methods

This is a cross-sectional study that was carried out in the pathology department from 1st January 2015 to 31st December 2023. Relevant data of all fibroepithelial lesions reported during the study period were retrieved from the medical records, tabulated, and analyzed. The Pearson chi-square test was used to determine the significant association between the various clinicopathological parameters of fibroepithelial lesions. A p-value of less than 0.05 was taken as statistically significant.

Results

Out of a total of 195 fibroepithelial lesions, 185 (95%) were fibroadenoma, 07 (3.5%) were phyllodes tumors, and three (1.5%) were fibroadenoma with tubular adenoma. The most common age group was 21 to 40 years, with the majority of phyllodes tumors being more than 5 cm in size compared to fibroadenomas. The association between the clinicopathological characteristics such as age of patients, tumor size, and histological grade was statistically insignificant in this study.

Conclusions

The implementation and usage of morphological diagnostic criteria will help in diagnosing and categorizing this broad group of fibroepithelial lesions, thereby facilitating appropriate treatment for patients.