# Unveiling the hidden culprit: Parathyroid adenoma induced recurrent renal calculus and pancreatitis—A case report

**Authors:** Aakash Kumar Pandit, Prajjwal Pokharel, Kabin Sapkota, Sanket Dhakal, Ram Narayan Kurmi, Mukesh Kumar Ranjan

PMC · DOI: 10.1002/ccr3.9248 · Clinical Case Reports · 2024-08-05

## TL;DR

A patient with recurring pancreatitis and kidney stones was found to have a parathyroid adenoma, showing the need for early diagnosis to prevent complications.

## Contribution

This case report highlights the rare but critical link between parathyroid adenoma and recurrent pancreatitis with renal stones.

## Key findings

- The patient had elevated PTH and calcium levels due to a parathyroid adenoma.
- Surgical removal of the adenoma normalized calcium and PTH levels.
- Early diagnosis prevented further episodes of pancreatitis and kidney stones.

## Abstract

This case report describes a 52‐year‐old patient presenting with recurrent episodes of pancreatitis and renal stones. Further investigation revealed hypocalcemia and elevated parathyroid hormone (PTH) levels, leading to diagnosis of a parathyroid adenoma. This case highlights the importance of considering primary hyperparathyroidism in patients with recurrent pancreatitis and renal stones, as early diagnosis and surgical intervention can prevent recurrence and reduce morbidity.

Primary Hyperparathyroidism secondary to Parathyroid adenoma, rarely presents as acute pancreatitis. A 38‐year‐young male with a history of recurrent renal stones referred from a local center, presented to the emergency services, with a diagnosis of acute pancreatitis and bilateral renal stones. Laboratory evaluation showed an elevated calcium level, elevated PTH levels, low vitamin D, and low phosphorus levels. CT scan done outside was suggestive of acute pancreatitis along with bilateral renal calculi. USG neck and MIBI scan done as a part of hypercalcemia evaluation showed presence of a right parathyroid adenoma. Parathyroid adenoma was later removed, and calcium and parathyroid levels were normal on subsequent follow ups.

## Linked entities

- **Chemicals:** calcium (PubChem CID 5460341), phosphorus (PubChem CID 139579)
- **Diseases:** pancreatitis (MONDO:0004982), primary hyperparathyroidism (MONDO:0010837), hypercalcemia (MONDO:0001566)

## Full-text entities

- **Genes:** PTH (parathyroid hormone) [NCBI Gene 5741] {aka FIH1, PTH1}
- **Diseases:** Primary Hyperparathyroidism (MESH:D049950), acute pancreatitis (MESH:D010195), Parathyroid adenoma (MESH:D010282), hypocalcemia (MESH:D006996), hypercalcemia (MESH:D006934), renal calculi (MESH:D007669)
- **Chemicals:** vitamin D (MESH:D014807), phosphorus (MESH:D010758), calcium (MESH:D002118)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11300816/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC11300816/full.md

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Source: https://tomesphere.com/paper/PMC11300816