# Antiphospholipid syndrome with major arterial thrombosis, presenting as pulmonary thromboembolism, cerebrovascular accident, and coronary artery disease: A case report and literature review

**Authors:** Aria Shirani, Morteza Daraei, Aryan Shirani

PMC · DOI: 10.1002/ccr3.9254 · Clinical Case Reports · 2024-08-05

## TL;DR

This case report discusses a patient with antiphospholipid syndrome who experienced multiple serious blood clots and highlights the importance of long-term anticoagulation therapy.

## Contribution

The paper presents a rare case of antiphospholipid syndrome with multiple arterial thromboses and emphasizes the need for long-term anticoagulation.

## Key findings

- Antiphospholipid syndrome can present with multiple arterial thromboses.
- Long-term anticoagulation is essential to manage the condition.
- Bleeding complications must be carefully monitored during treatment.

## Abstract

Antiphospholipid syndrome is an immunopathologic disorder that should be considered in all patients with recurrent and/or unexplained thromboembolic events. Antiphospholipid antibodies are diagnostic markers, and anticoagulation therapy is the therapeutic and preventive strategy. Long‐term anticoagulation therapy is necessary, with careful attention to potential bleeding complications.

## Linked entities

- **Diseases:** antiphospholipid syndrome (MONDO:0017278), cerebrovascular accident (MONDO:0005098), coronary artery disease (MONDO:0005010)

## Full-text entities

- **Diseases:** Antiphospholipid syndrome (MESH:D016736), arterial thrombosis (MESH:D002341), thromboembolic events (MESH:D013923), coronary artery disease (MESH:D003324), pulmonary thromboembolism (MESH:D011655), bleeding (MESH:D006470), cerebrovascular accident (MESH:D020521)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11299070/full.md

## References

22 references — full list in the complete paper: https://tomesphere.com/paper/PMC11299070/full.md

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Source: https://tomesphere.com/paper/PMC11299070